The mothers of cerebral palsy children tend to have poor quality of life, because there are parenting challenges. During this time program of rehabilitation more focusedon children with cerebral palsy than the caregiver. This study tried to describe the quality of life mothers, with CP children. Subjects were 32 mothers, from Kulon Progo regency, which parenting CP children. Quantitative descriptive methods used in this study. The results showed that high quality of life owned by many mothers with incomes of more than  Rp 40.000 per day, it does not work, at least a high school education, aged about 31 years to 46 years, and have been married for 9 years.